Bleaching of Microcrystalline Cellulose Produced by Gas-Phase Hydrolysis

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UDС

661.728

DOI:

https://doi.org/10.37482/0536-1036-2021-6-173-183

Abstract

One of the main consumers of microcrystalline cellulose (MCC) is the pharmaceutical industry, where MCC is used as a binder and filler in direct compression of tablets. MCC is produced by acidic hydrolysis of cellulose, which usually results in a decrease in whiteness. This is due to the destruction of sugars formed during hydrolysis and the subsequent formation of colored products. The composition and properties of these products depend on the method of hydrolysis, acid concentration, temperature, and process duration. One of the most promising methods for producing MCC is gas-phase hydrolysis of cellulose with hydrogen chloride gas-air mixtures. The method has a high rate of hydrolysis, low reagent and energy consumption. The requirements of the pharmaceutical industry determine the need to produce MCC with high whiteness. The research purpose is to select bleaching modes for MCC using sodium hypochlorite and hydrogen peroxide as bleaching agents. MCC produced by gas-phase hydrolysis of bleached wood pulp was used during the study. The whiteness and intensity of the yellow tint of MCC in the bleaching process were determined by digital colorimetry on a flatbed scanner. The paper shows that sodium hypochlorite and hydrogen peroxide allow achieving the whiteness not less than 90 % and the intensity of the yellow tint not more than 3 standard units. High-quality bleaching can be carried out even for MCC samples with an initial whiteness of about 40 %. The most effective bleaching agent is sodium hypochlorite when the pH of the bleaching solution is 2–3. Hydrogen peroxide also provides high whiteness of MCC at pH of 10–11. However, the consumption of active oxygen (AO) for bleaching is more than three times higher in comparison with the consumption of active chlorine (ACh). It was found that the dyes of MCC produced by gas-phase hydrolysis consist of two chromophore groups that decolorize at different rates. The easily oxidized group of components makes up about 90 % of the total amount of dyes, and the resistant to oxidation components make up about 10 % and determine the intensity of the yellow tint of MCC. The modes of bleaching MCC with sodium hypochlorite and hydrogen peroxide to product samples with whiteness comparable to that of imported samples were determined.

Authors

Alexander I. Sizov¹, Candidate of Engineering, Assoc. Prof.; ResearcherID: AAI-2030-2020, ORCID: https://orcid.org/0000-0001-9412-5557
Sergey D. Pimenov¹, Postgraduate Student; ResearcherID: AAC-9435-2020,  ORCID: https://orcid.org/0000-0001-6042-0021
Anastasia D. Stroiteleva², Analytical Chemist; ResearcherID:AAL-9152-2020, ORCID: https://orcid.org/0000-0002-9031-0007
Katherine D. Stroiteleva², Analytical Chemist; ResearcherID: AAL-9208-2020, ORCID: https://orcid.org/0000-0001-5888-9349

Affiliation

¹Saint-Petersburg State Forest Technical University named after S.M. Kirov, Institutskiy per., 5, Liter U, Saint Petersburg, 194021, Russian Federation; e-mail: sizov.alex@gmail.com, chudopim@mail.ru
²OOO “Kristatsel”, ul. Shakhmatova, 10, оf. 131, Saint Petersburg, 198504, Russian Federation; e-mail: anastasia_stroiteleva1019@mail.ru,  atherine_stroiteleva1007@mail.ru

Keywords

bleaching, microcrystalline cellulose, bleaching agents, sodium hypochlorite, hydrogen peroxide, gas-phase hydrolysis of cellulose

For citation

Sizov A.I., Pimenov S.D., Stroiteleva A.D., Stroiteleva K.D. Bleaching of Microcrystalline Cellulose Produced by Gas-Phase Hydrolysis. Lesnoy Zhurnal [Russian Forestry Journal], 2021, no. 6, pp. 173–183. DOI: 10.37482/0536-1036-2021-6-173-183

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